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API development and new technology equipment (1)
Updated:2011-11-09 12:16:13    Copyfrom:sdhuge    Hits: Notice: Undefined index: clicknum in /data/user/htdocs/en/APP/special/view.php on line 72
Abstract: machinery and equipment from the API level of technology, describes our API equipment should be based on new changes in the global market, to strengthen the application of new technologies: research and environmental protection and energy-saving safety technology, the development of automation technology, to strengthen the application of virtual technology, modular design.


Keywords: API devices; new technologies; development; application
1 Introduction
API China pharmaceutical machinery and equipment is equipped with one of 8 categories of products, including response equipment, tower equipment, crystallization equipment, separation equipment, filtration equipment, extraction equipment, distillation equipment, heat exchanger, evaporator equipment, drying equipment, sieve separation equipment, storage equipment and sterilization equipment. As we all know, China is the largest producer of bulk drugs, bulk drugs, but not the production of power. The reasons are many, but very important reason is that raw material drug production equipment and new technology applications and international high-level there is a certain gap. Therefore, to improve the quality of our raw material drug production, in addition to the hardware and software to increase productivity from the corporate control standards should be based on the new changes in the global market, to enhance the device API application of new technologies, the real line with international standards.

2 application of new technologies
2.1 of environmental protection and energy saving
In March 2007, State Environmental Protection Administration announced six 066 key industrial pollution control companies, pharmaceutical companies accounted for 117, to the fermentation raw material drug production-sized class, and some companies who were discontinued because of environmental problems [1]. So, tapping the potential energy, improve economic efficiency will be the API manufacturer for some period of time and important work. Below are several examples to illustrate practical applications in environmental protection and energy conservation, the API development and equipment technology.

2.1.1 Freeze-drying Equipment
2.1.1.1 liquid nitrogen and vacuum freeze-drying machine
Freeze dryer for drying and cooling systems provide cooling condenser vacuum source. Among them, the more common freeze dryer refrigeration compressor, compressor parts, but his heart due to various factors often lead to many failures, need regular maintenance. Today, the new liquid nitrogen and vacuum freeze-drying machine to solve this problem, shown in Figure 1, which effectively reduces the probability of failure of the refrigeration system.

Liquid nitrogen freeze dryer is the use of liquid nitrogen as a cold source to the cooling system of a freeze dryer, freeze dryer with a different general, the cold source of liquid nitrogen. The air contains 78% nitrogen, therefore, very convenient to take the system of liquid nitrogen can be said that an inexhaustible green energy. In addition, the use of liquid nitrogen refrigeration, compressors and water coolers are no longer used, so, low noise, reliable operation without cardiac component maintenance, repair simple, while more than 50% reduction in power consumption [2], which will long-term economic benefits to the enterprise.
2.1.1.2 new freeze-drying equipment sterilization - disinfection of H2O2 at room temperature
In order to improve the health status of production lines, up to a certain sterile conditions to avoid contamination, Vapovac freeze-drying equipment for the disinfection of equipment, the company offers a new sterilization process [3] - the role of the existing system under vacuum, the H2O2 gas pipeline to be transported to the freeze dryer, make hydrogen peroxide disinfection. This disinfection technology and other significant difference is that the process, gaseous H2O2 sterilization process is carried out under vacuum at room temperature and, therefore, has the following characteristics: (1) and other chemical disinfection methods, reducing manpower, but also reduces the the risk of contaminated equipment, and do not produce carcinogenic by-products or lead to mutations; (2) No need to over-pressure explosion-proof container, reducing the use of the corresponding input costs; (3) without using any additional gas distribution equipment, disinfectants can be very well distributed in the dryer in each corner to achieve a full range of disinfection (this is not an ordinary steam sterilization are achieved); (4) with steam sterilization compared to each sterilization cycle to reduce the cost of 20% and 50% of the disinfection time.